Theme

・Astrocyte-Neuron interactions in expression of neural function
・Molecular mechanisms of astrocyte
・The effects of neuro-protective and neuro-regenerative factors derived
   from glial cell
・The pathophysiology of rheumatoid arthritis

Erythropoietin suppressed the LPS-induced phagocytic activity of BV-2 microglial cells and revealed neuroprotective effect.

Member

Professor
Kiyofumi Asai
Assistant professor
Yohei Kawaguchi
Technical staff
Seiko Ukai

Publications

  • Three-dimensional spheroid culture induces apical-basal polarity and the original characteristics of immortalized human renal proximal tubule epithelial cells. Exp Cell Res 1;404(1):112630 (2021)
  • N-acetyl-seryl-aspartyl-lysyl-proline:A new potential serum biomarker of rheumatoid arthritis. Medical Mass Spectrometry Vol. 5 No. 1 (2021)
  • Pyogenic tenosynovitis of the wrist due to Corynebacterium striatum in a patient with dermatomyositis: A case report. Medicine (Baltimore) Jan;99(3):e18761 (2020)
  • The Janus kinase inhibitor tofacitinib inhibits TNF-α-induced gliostatin expression in rheumatoid fibroblast-like synoviocytes. Clin Exp Rheumatol 36: 559-567 (2018)
  • Mithramycin has inhibitory effects on gliostatin and matrix metalloproteinase expression induced by gliostatin in rheumatoid fibroblast-like synoviocytes. Mod Rheumatol 28: 495-505 (2018)
  • Neuroprotective erythropoietin attenuates microglial activation, including morphological changes, phagocytosis, and cytokine production. Brain Res 1662: 65-74 (2017)
  • CXCR4+ CD45- Cells are Niche Forming for Osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 Signaling Pathways in Bone Marrow. Stem Cells 34: 2733-2743 (2016)